Vol 2, No 1-2 (2019)

We report a case of small-cell neuroendocrine carcinoma of the major duodenal papilla in a 62-year-old female patient with mechanical jaundice developed from the heterotopic pancreatic tissue with a transitional area from ectopic tissue to the tumor. This article also reviews the literature on pancreatic ectopic tissue in various organs and tumors developing from this tissue. Most commonly, an ectopic pancreas is seen in the stomach (24-38 %); less common locations include the duodenum/major duodenal papilla (9-36 %) and jejunum (0.5-27.0 %). Rarely, pancreatic ectopic tissue can be found in the colon, Meckel’s diverticulum, umbilical region, liver, gallbladder, intestinal mesenteries, rectum, and pelvic organs. Current literature describes various types of tumors originating from ectopic pancreatic tissue, including mixed tumors (carcinoid plus signet ring cell gastric carcinoma, intraductal papillary mucinous tumor plus adenocarcinoma, and adenocarcinoma plus acinar cell tumor), adenocarcinomas, solid pseudopapillary tumors, anaplastic carcinomas, and neuroendocrine tumors.

A draft of recommendations on cytomorphological diagnosis of the urinary tract pathology is presented. The paper highlights the main points of the pre-analytical stage: the obtaining of the material, its preparation and staining. The categories of the Paris System are presented, the main cytomorphological criteria for assessing the urinary pathology in cytopreparations are noted.