<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Oncopathology</journal-id><journal-title-group><journal-title xml:lang="en">Oncopathology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкопатология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2618-7019</issn><issn publication-format="electronic">3034-3534</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">708417</article-id><article-id pub-id-type="doi">10.17650/2619-7019-2018-1-1-18-23</article-id><article-id pub-id-type="edn">MGTDIZ</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews and lectures</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обзоры и лекции</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Actual problems of the terminology used in histological diagnostics of melanocytic skin neoplasms</article-title><trans-title-group xml:lang="ru"><trans-title>Актуальные проблемы терминологии, используемой в гистологической диагностике меланоцитарных новообразований кожи</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mordovtseva</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Мордовцева</surname><given-names>В. В.</given-names></name></name-alternatives><email>gveesha@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sergeev</surname><given-names>Yu. Yu.</given-names></name><name xml:lang="ru"><surname>Сергеев</surname><given-names>Ю. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>abv@abvpress.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gorban'</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Горбань</surname><given-names>Н. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>abv@abvpress.ru</email><xref ref-type="aff" rid="aff4"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Institute for Medical and Social Technologies, Moscow State University of Food Production</institution></aff><aff><institution xml:lang="ru">Институт медико-социальных технологий ФГБОУВО «Московский государственный университет пищевых производств»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Laboratory Gemotest LLC</institution></aff><aff><institution xml:lang="ru">ООО «Лаборатория Гемотест»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Society of Dermoscopy and Optical Skin Diagnostics</institution></aff><aff><institution xml:lang="ru">Общество дерматоскопии и оптической диагностики кожи</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">N.N. Burdenko Main Military Clinical Hospital, Ministry of Defence of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Главный военный клинический госпиталь им. акад. Н.Н. Бурденко» Минобороны России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-02-18" publication-format="electronic"><day>18</day><month>02</month><year>2018</year></pub-date><volume>1</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>18</fpage><lpage>23</lpage><history><date date-type="received" iso-8601-date="2026-06-09"><day>09</day><month>06</month><year>2026</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, ABV-Press</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, АБВ-пресс</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">ABV-Press</copyright-holder><copyright-holder xml:lang="ru">АБВ-пресс</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://oncopathology.abvpress.ru/2618-7019/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://oncopathology.abvpress.ru/2618-7019/article/view/708417">https://oncopathology.abvpress.ru/2618-7019/article/view/708417</self-uri><abstract xml:lang="en"><p>Diagnosis of melanocytic neoplasms is one of the most challenging problems in pathomorphology. This can be explained by a significant diversity of melanocytic nevi and skin melanoma, unclear diagnostic criteria, and varying severity of signs in different neoplasms. A discrepant expert opinion and low reproducibility of certain diagnoses pose a significant problem. However, there is a particular type of diagnostic errors associated with misinterpretation and incorrect practical application of fundamental terms. The article is devoted to the analysis of the most common errors of this type.</p></abstract><trans-abstract xml:lang="ru"><p>Диагностика меланоцитарных новообразований является одним из самых сложных разделов патоморфологии. Это объясняется видовым разнообразием меланоцитарных невусов и меланомы кожи, отдельными неопределенными диагностическими критериями, а также неодинаковой степенью выраженности этих признаков в разных образованиях. Расхождения мнений и низкая воспроизводимость отдельных диагнозов представляют сегодня реальную проблему. Однако есть особый тип диагностических ошибок, связанный с неверной трактовкой и практическим применением основополагающей терминологии. Разбору наиболее часто встречающихся ошибок данного типа посвящена статья.</p></trans-abstract><kwd-group xml:lang="en"><kwd>melanoma</kwd><kwd>dysplasia</kwd><kwd>Lentigo</kwd><kwd>lentiginous hyperplasia</kwd><kwd>levels of invasion</kwd><kwd>phases of tumour growth</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>меланома</kwd><kwd>дисплазия</kwd><kwd>лентиго</kwd><kwd>лентигинозная гиперплазия</kwd><kwd>уровни инвазии</kwd><kwd>фазы роста</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Clark WH.Jr. A classification of malignant melanoma in man correlated with histogenesis and biologic behavior. In: Advances in Biology of the Skin, Vol. 8, The Pigmentary System. Eds.: I.w. Montagna, F. Hu. London: Pergamon Press Ltd., 1967. Pp. 621-647.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Clark W.H.Jr., From L., Bernardino E.A., Mihm M.C. The histogenesis and biologic behavior of primary human malignant melanomas of the skin. Cancer Res 1969;29(3):705-27. PMID: 5773814.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Clark W.H.Jr., Evans H.L., Everett M.A. et al. Early melanoma. Histologic terms. Am J Dermatopathol 1991;13(6):579-82. PMID: 1805653.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Clark W.H.Jr., Hood A.F., Tucker M.A., Jampel R.M. Atypical melanocytic nevi of the genital type with a discussion of reciprocal parenchymal-stromal interactions in the biology of neoplasia. Hum Pathol 1998;29(1 Suppl 1):S1-24. PMID: 9445124.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Clark WH.Jr. The dysplastic nevus syndrome. Arch Dermatol 1988;124(8):1207-10.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Haenssle H.A., Mograby N., Ngassa A. et al. Association of patient risk factors and frequency of nevus-associated cutaneous melanomas. JAMADermatol 2016;152(3):291-8. PMID: 26536613. DOI: 10.1001/jamadermatol.2015.3775.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Marks R., Dorevitch A.P., Mason G. Do all melanomas come from "moles"? A study of the histological association between melanocytic naevi and melanoma. Australas J Dermatol 1990;31(2):77-80. PMID: 2095738.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Fernandes N.C. The risk of cutaneous melanoma in melanocytic nevi. An Bras Dermatol 2013;88(2):314-5. PMID: 23739702. DOI: 10.1590/S0365-05962013000200030.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Rhodes A.R., Melski J.W. Small congenital nevocellular nevi and the risk of cutaneous melanoma. J Pediatr 1982;100(2):219-24. PMID: 7057329.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Maia M., Russo C., Ferrari N. et al. Small congenital melanocytic nevus and the risk of developing melanoma. An Bras Dermatol 2003;78(2):189-95. DOI: 10.1590/ S0365-05962003000200006.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Clark W.H., Goldstein A.M., Tucker M.A. Prospective for cutaneous malignant melanoma. Considerations of the precursor state and heritability. Br Med Bull 1995;51(3):717-46. PMID: 7552090.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Сергеев Ю.Ю., Мордовцева В.В., Сергеев В.Ю. Меланома кожи в практике дерматолога. Фарматека 2017;17(350): 67-73.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Sergeev Yu.Yu., Mordovtseva V.V., Sergeev V.Yu. Skin melanoma in dermatological practice. Farmateka // Pharmateca 2017;17(350):67-73. (In Russ.).</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Clark W.H.Jr. The nature of cancer: morphogenesis and progressive (self)-disorganization in neoplastic development and progression. Acta Oncol 1995;34(1):3-21. PMID: 7865232.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Clark W.H.Jr. From the melanocyte to melanoma to tumor biology. Adv Cancer Res 1994;65:113-40. PMID: 7879663.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Мордовцева В.В. Понятие о дисплазии применительно к меланоцитарным невусам. Пластическая хирургия и косметология 2013;1:78-81.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Mordovtseva V.V. Concept of dysplasia in terms of melanocytic nevi. Plasticheskaya khirurgiya i kosmetologiya = Plastic Surgery and Cosmetology 2013;1:78-81. (In Russ.).</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Hurwitz R.M., Tavel M.E. The mythical concept and untoward consequences of a diagnosis of dysplastic nevus: an overdue tribute to A. Bernard Ackerman, MD. Dermatol Pract Concept 2015;5(1):31-4. PMID: 25692079. DOI: 10.5826/dpc.0501a05.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Ackerman A.B. Mythology and numerology in the sphere of melanoma. Cancer 2000;88(3):491-6. PMID: 10649238.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Bastos Junior Cde S., Pineiro-Maceira J.M., Moraes F.M. Desmoplastic melanoma associated with an intraepidermal lentiginous lesion: case report and literature review. An Bras Dermatol 2013;88(3):408-12. PMID: 23793214. DOI: 10.1590/abd1806-4841.20131817.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Clark W.H.Jr., Mihm M.C. Lentigo maligna and lentiqo-maligna melanoma. Am J Pathol 1969;55:39-67.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Suffin S.C., Waisman J., Clark W.H.Jr., Morton D.L.Comparison of the classification by microscopic level (stage) of malignant melanoma by three independent groups of pathologists. Cancer 1977;40(6):3112-4. PMID: 589569.</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Elder D., Murphy G. Atlas of tumor pathology: melanocytic tumors of the skin. Bethesda: Armed Forces Institute of Pathology, 1991. 212 p.</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>World Health Organization Classification of Tumours 2006. 3rd edn. Eds.: P.E. LeBoit, G. Burg, D. Weedon, A. Sarasain. Lyon: IARC Press, 2006.</mixed-citation></ref></ref-list></back></article>
